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Podocytes

Podocyte. Podocytes are rich sources of VEGF, which appears to attract endothelial precursors into the vascular clefts of the S-shaped bodies and thereby promote glomerular capillary formation.119,124,125 VEGF and VEGFR expression is regulated by hypoxia-inducible factors that are activated by tissue hypoxia The modified epithelial cell of the visceral layer of glomerular capsule in the renal corpuscle, attached to the outer surface of the glomerular capillary basement membrane by cytoplasmic foot processes (pedicels); believed to play a role in the ultrafiltration of blood

Podocyte - an overview ScienceDirect Topic

Podocytes are highly specialized cells of the kidney glomerulus that wrap around capillaries and that neighbor cells of the Bowman's capsule. When it comes to glomerular filtration, podocytes play an active role in preventing plasma proteins from entering the urinary ultrafiltrate by providing a barrier comprising filtration slits between foot. Podocytes are highly specialized cells of the kidney glomerulus that wrap around capillaries and that neighbor cells of the Bowman's capsule. When it comes to glomerular filtration, podocytes play. Ultrastructure of the Cell: podocytes and glomerular capillaries UIUC Histology Subject 1400; podocyte.ca at Samuel Lunenfeld Research Institute; فسيولوجيا: 7/7ch04/7ch04p09 - أساسيات فسيولوجيا الإنسان; صور نسيجية: 22402loa — نظام تعلم علم الأنسجة في جامعة بوسط Podocytes have pedicles which wrap around the: a. Afferent arterioles b. Glomerular capillaries c. Efferent arterioles d. Renal tubules The filtration slits.

Podocytes attach to the GBM exclusively by foot processes (FPs) or foot process equivalents called basal ridges (Ichimura et al., 2015). Thus, the entire outer aspect of the GBM is completely covered by FPs bridged by the slit diaphragm forming a completely interconnected homogenous cell layer (Fig. 1). GBM and FPs together may be considered as. PDF | This commentary highlights the article by Hara et al that discusses the clinical implications of mitotic catastrophe in podocyte health during... | Find, read and cite all the research you. We would like to show you a description here but the site won't allow us

BioLegend podocytes Podocytes, supplied by BioLegend, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and mor podocytes. Ji Wîkîferheng. Jump to navigation Jump to search. Inglîz. Podocytes are highly specialised, terminally differentiated cells with a complex cellular structure. They are a critical component of glomerular filtration. Cell cycle control, growth arrest and differentiation are key to the in-vivo biology of podocytes. The conditionally immortalised podocyte cell line allows an in-vitro process of maturation.

Podocytes definition of Podocytes by Medical dictionar

  1. Podocytes are structurally and functionally complex cells which play a key role in the normal prevention of proteinuria. In many renal diseases, including FSGS and diabetic nephropathy, podocyte injury/loss is a major pathogenetic and prognostic factor
  2. The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A. Nat Med 2008; 14:931. Ransom RF, Lam NG, Hallett MA, et al. Glucocorticoids protect and enhance recovery of cultured murine podocytes via actin filament stabilization
  3. Cyanidin-3-O-glucoside attenuates high glucose-induced podocytes dysfunction by inhibiting apoptosis and promoting autophagy via activation of SIRT1/AMPK pathway. Oct 15, 2020. Diabetic nephropathy (DN) is a common and complicated chronic kidney disease around the world. To elucidate and find effective therapies of DN is of vital importance
  4. Podocytes, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 93/100, based on 87 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and mor
  5. ed. In this issue, Naik et al. use non-invasive urinary mRNA analysis to demonstrate that higher podocyte stress and detachment are associated with higher MAP in the normal.

Podocyte definition of podocyte by Medical dictionar

Podocytes - highly specialised epithelial cells that wrap around the capillaries of the glomerulus (filtration takes place through the the filtration slits between the feet of the podocytes) Endothelial cells of the capillaries are freely permeable to everything in the blood except red blood cells and platelets Results Using human podocytes and a mouse model, we demonstrated that AGEs activate Notch1 signaling in podocytes and provoke EMT. Inhibition of RAGE and Notch1 by FPS-ZM1 (N-Benzyl-4-chloro-N-cyclohexylbenzamide) and DAPT (N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenyl glycine t-butylester), respectively, abrogates AGE-induced Notch activation and EMT

Podocytes

  1. Podocyte: A cell with branching tentacle-shaped extensions that constitutes the barrier through which blood is filtered in the glomerulus of the kidney. From the Greek pod- (foot) + -cyte (cell)
  2. Podocytes are highly differentiated cells with limited capability to undergo cell division in the adult, and the loss of podocytes is a hallmark of progressive kidney disease. The function of podocytes is based largely on the dynamic regulation of their complex cell architecture, in particular the FP structure
  3. Podocytes is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity
  4. Podocytes form unique cytoplasmic extensions, foot processes, which attach to the outer surface of the glomerular basement membrane and interdigitate with neighboring podocytes to form the slit.

Pedicels (podocytes) 3b. Podocyte or sometimes called Bowman's cells 4. Bowman's space (urinary space) 5a. Mesangium - Intraglomerular cell 5b. Mesangium - Extraglomerular cell 6. Granular cells (Juxtaglomerular cells) 7. Macula densa 8. Myocytes (smooth muscle) 9. Afferent arteriole 10. Glomerulus Capillarie Podocytes from Lmx-1b knock-out mouse retained a cuboidal shape and did not form foot processes and slit diaphragms. These podocytes showed a reduced expression of the α 4-chain of collagen IV and the slit diaphragm proteins CD2AP and podocin. In addition, there are Lmx-1b binding sites in the putative regulatory regions of both CD2AP and NPHS2 podocytes in vivo (positive for WT-1, synaptopodin, and podocalyxin). On the other hand, cells from encapsulat-ed glomeruli fell morphologicaly into two distinct cellu-lar types: polygonal cobblestone-like cells localized in the colony centers and large irregularly shaped cells occupy- ing the colony peripheries..

Podocytes are considered the primary source of the GBM components laminin β2 and the collagen α3α4α5 (IV) network. 34,35. Collagen IV is the major structural component of the GBM. Collagen IV forms a highly cross-linked network to which the other components of the GBM can attach. There are six collagen IV isoforms, α1-α6 Podocytes are an integral part of the glomerular filtration barrier, a structure that prevents filtration of large proteins and macromolecules into the urine. Podocyte function is dependent on actin cytoskeleton regulation within the foot processes, structures that link podocytes to the glomerular basement membrane. Actin cytoskeleton dynamics in podocyte foot processes are complex and. The podocyte is the most differentiated cell type in the glomerulum, which forms a crucial component of the glomerular filtration barrier. It has been assumed that podocyte foot processes counteract the elastic force of the glomerular basement membrane and that vasoactive hormones may regulate the contractile state of their foot processes and thereby modulate the ultrafiltration coefficient K f Find the perfect podocytes stock photo. Huge collection, amazing choice, 100+ million high quality, affordable RF and RM images. No need to register, buy now The podocytes were initially cultured in vitro at the permissive temperature of 33°C and then differentiated over the course of 12 days at the nonpermissive temperature of 37°C. Differentiated podocytes demonstrated increased cell size and finger-like foot process extensions, as evidenced by phase-contrast microscopy

Recent insights have defined the central role of podocytes both in rare genetic diseases and as a general determinant of the progression of human glomerular diseases. In a recent issue of Nature, Weavers et al. described a podocyte-like cell type in Drosophila, the nephrocyte, that closely resembles mammalian podocytes, including the nephrin-based slit diaphragm Results: Using podocytes cultured on an advanced decellularized matrix, we demonstrated that in the presence of IL-23 the expression of IL-23 receptor on the surface membrane of podocytes increases significantly followed by increased levels of phosphorylated STAT3. We found that phosphorylated STAT3 associated with Rac1 and this resulted in. Hi there! Below is a list of podocytes words - that is, words related to podocytes. There are 86 podocytes-related words in total, with the top 5 most semantically related being nephrin, ultrafiltration, glomerulus, water and urine.You can get the definition(s) of a word in the list below by tapping the question-mark icon next to it The 12 th International Podocyte Conference will begin on Wednesday afternoon, May 30 and end on Saturday noon, June 2 nd, 2018.Sessions will take place at the Marriott Chateau Champlain, Montreal, Quebec, Canada. The conference is open to participants from all over the world and will be conducted in English Podocytes wound healing and transwell migration assay were assessed by the ways described previously. 23 Three independent experiments were conducted for each assay to summarize the mean and standard deviation of data. 2.11 Statistics. All data were presented as the mean ± SEM. The software GraphPad Prism was applied for statistical analysis

Podocyte EM - Yale Universit

OVA antigen presentation by podocytes was also validated using human podocytes. Furthermore, OVA antigen‐presenting mouse podocytes were able to activate OT‐I mouse T cell proliferation and inflammatory cytokine secretion, which in turn, caused podocyte injury and apoptosis Podocytes Kidney Tubules, Collecting Kidney Glomerulus Embryonic Stem Cells Stem Cells Bowman Capsule Glomerular Filtration Barrier Cell-Derived Microparticles Kidney Endothelium, Vascular. Organisms 2. Abelmoschus Viridiplantae. Diseases 11 Podocytes are specialized actin-rich epithelial cells that line the kidney glomerular filtration barrier. The interface between the podocyte and the glomerular basement membrane requires integrins, and defects in either α 3 or β 1 integrin, or the α 3 β 1 ligand laminin result in nephrotic syndrome in murine models. The large cytoskeletal. The team had previously found podocytes present in patients with pre-eclampsia when they gave birth. (open, save, copy) bbc.co.uk. Identifying genes and proteins that are active in podocytes will help scientists understand how they work. (open, save, copy) sciencedaily.co

Podocytes - structure and function - YouTub

  1. ally differentiated cells of the kidney glomerulus, which have a key role in glomerular development and maintenance ().The cytoskeletal dynamics and structural plasticity of podocytes, as well as the function of received and transmitted signals, are important for glomerular filtration and thus for renal function
  2. gle with the capillaries and filter the blood, maintaining the proper water and salt balance. Key takeaway Injury to the blood-filtering cells known as podocytes can cause kidney failure. This study finds a master genetic program that triggers self-repair and could point to.
  3. ally differentiated, and cannot be cultured for more than 1 or 2 passage without loss of their particular traits (like foot processes and expression of slit diaphragm proteins). Advantage
  4. tein tyrosine kinases and phosphatases participate in many, if not all, aspects of cellular function by turning on or off multiple signaling cascades and podocytes are no exception. Modulation of tyrosine residue phosphorylation of podocyte factors such as nephrin, vascular endothelial growth factor, insulin receptors and substrates has been shown to promote podocyte damage and cell death that.
  5. Diabetes is increasing in prevalence and is the leading cause of end-stage renal disease in the United States. Diabetic kidney disease is considered a proteinuric glomerular disease. Although the glomerulus is composed of various cell types, research suggests that podocytes are critical to overall glomerular health. Podocyte injury has been identified as a pivotal event resulting in.
  6. Podocytes present a unique 3D architecture specialized for glomerular filtration. However, several 3D morphological aspects on podocyte development remain partially understood because they are difficult to reveal using conventional scanning electron microscopy (SEM). Here, we adopted serial block-face SEM imaging, a powerful tool for analyzing the 3D cellular ultrastructure, to precisely.
ANAT2241 Urinary System - Embryology

[The role of podocytes in normal glomerular function and

  1. ary data also reported a.
  2. Podocytes are pivotal in establishing the selective permeability of the glomerular filtration barrier. Recently, we showed that an increase of the intracellular calcium ion concentration [Ca 2+] causes a rapid and transient actin reset (CaAR) measurable through live imaging microscopy using lifeact‐mCherry as an actin dye in different cell types including the podocyte
  3. เยื่อกรองจะยอมให้ของเหลวและสารโมเลกุลเล็ก ๆ ที่ละลายในพลาสมาผ่านออกมาได้ ได้แก่ น้ำ กลูโคส กรดอะมิโน วิตามิน เกลือแร่ เช่น.
  4. Podocytes are target cells in the glomerulus for various stimuli, and podocyte injury occurs to varying degrees in pathological conditions. Podocytes are located on the outer surface of the glomerular basement membrane; thus, injured podocytes or related structures appear in the urine if injury to the cell is serious enough
  5. podocytes. Cells of the visceral epithelium that closely invest the network of glomerular capillaries in the kidney. Most of the cell body is not in contact with the.

(a) Podocytes stably expressing GFP-LC3 were pretreated with 2 mmol/L 3-MA for 1 hour, treated with 150 μmol/L palmitic acid for 24 hours and then analyzed by fluorescence microscopy (400×) Start studying A&P CHAPTER 4 TEST BANK. Learn vocabulary, terms, and more with flashcards, games, and other study tools

Histology Learning System [ Ultrastructure of the Cell, podocytes and glomerular capillaries, filtration barrier The Ca2+-activated phospholipid scramblase and ion channel TMEM16F is expressed in podocytes of renal glomeruli. Podocytes are specialized cells that form interdigitating foot processes as an essential component of the glomerular filter. These cells, which participate in generation of the primary urine, are often affected during primary glomerular diseases, such as glomerulonephritis and. Abstract Purpose of review In this review, we discuss the role of endocytosis, a fundamental process internalizing molecules from the plasma membrane, and its critical importance in podocyte biology. Recent findings Endocytic clathrin and nonclathrin-coated pits have been visualized in podocytes using electron microscopy, but the functional biological relevance has not been well defined Introduction. Albuminuria is a hallmark of nephropathy, usually caused by a deterioration in the integrity of the glomerular filtration barrier (Schiessl et al., 2016).The glomerular filtration barrier consists of a porous endothelium, basement membrane and podocytes

A Review of Podocyte Biolog

Rac1, a Rho family member, is ubiquitously expressed and participates in various biological processes. Rac1 expression is induced early in podocyte injury, but its role in repair is unclear. To. Diabetic kidney disease (DKD) is a major cause of end-stage renal disease (ESRD), and therapeutic strategies for delaying its progression are limited. Loss of podocytes by apoptosis characterizes the early stages of DKD. To identify novel therapeutic options, we investigated the effects of Xuesaitong (XST), consisting of total saponins from Panax notoginseng, on podocyte apoptosis in.

Glomerular visceral epithelial cells, also termed podocytes, are highly specialized epithelial cells that cover the outer aspect of the glomerular basement membrane. Recent studies point to an important role of podocytes in the physiology and pathophysiology of the glomerulus. This review summarizes the structure-function relationships of podocytes Postmitotic podocytes are essential components of the three-layered glomerular filtration barrier of the kidney, and we have demonstrated that podocyte function is regulated through signalling at a highly specialized cell junction, called the slit diaphragm. Over the past decade my team has pioneered the concept that podocytes are master. The world's first wiki where authorship really matters. Due credit and reputation for authors [authorship tracking technology]. Imagine a global collaborative knowledge base for original thoughts [Nature Genetics]

Podocytes Highly differentiated epithelial cells of the visceral layer of BOWMAN CAPSULE of the KIDNEY. They are composed of a cell body with major CELL SURFACE EXTENSIONS and secondary fingerlike extensions called pedicels Podocytes and Glomerular Filtration . 3 years ago. Glycocalyx & Fenestrae . 5 years ago. Glomerulus fly-through fx sequence . 7 years ago. Glomerulus fly-through . 7 years ago. What are Tags? Tags are keywords that describe videos. For example, a video of your Hawaiian vacation might be tagged with Hawaii, beach, surfing, and sunburn.. Podocytes cells are the cells which occur in the visceral layer of the Bowman's capsule. These are specialized epithelial cells that reside in the visceral layer of the capsule. It plays an important role in glomerular filtration. It combines with the endothelial cells of the glomerular capillary loop and the glomerular basement membrane they.

What does podocytes mean? - definition

Contribute to monashmicroimaging/podocytes development by creating an account on GitHub Podocyte Scanning EM The scanning EM demonstrates the branched structure of podocytes and how foot processes of adjacent podocytes interface to form filtration slits around a capillary Thus, podocytes can only increase their size to compensate for further glomerular expansion during glomerular development. Podocytes need to cover the surface of the glomerular basement membrane (GBM); after the terminal differentiation of podocytes, any further increase in filtration area will require a compensatory cell growth of podocytes The aim of this study was to investigate the structural characteristics of podocytes and endothelial cells in diabetic nephropathy. We studied 18 patients with type 1 diabetes (seven normoalbuminuric, six microalbuminuric, and five proteinuric), and six normal control subjects. Groups were not different for age. Type 1 diabetic groups were not different for diabetes duration or age at diabetes.

(PDF) Podocytes - ResearchGat

View Academics in Podocytes on Academia.edu Podocytes are an important part of the glomerular filtration barrier and the key player in the development of proteinuria, which is an early feature of complement mediated renal diseases. Complement factors are mainly liver-born and present in circulation. Nevertheless, there is a growing body of evidence for additional sites of complement protein synthesis, including various cell types in the. In order to produce mature podocytes, Samira Musah, Ph.D., a former Postdoctoral Fellow in the laboratory of Founding Director Donald Ingber, M.D., Ph.D., who is currently an Assistant Professor of Biomedical Engineering at Duke University, first created nephron progenitor-like cells from iPS cells, and then exposed them to a new cell culture. Podocytes were identified by their expression of the podocyte markers WT1, synaptopodin, and nephrin. Podocytes were cultured on collagen I-coated plates at 33°C in a growth-permissive medium of RPMI supplemented with 10% FBS and 100 units per ml of recombinant mouse IFNγ (a gift from Robert Schreiber, Washington University, St. Louis, MO)

خلية رجلاء - ويكيبيدي

Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip Samira Musah1,2, Nikolaos Dimitrakakis1, Diogo M. Camacho 1, George M. Church1,2 and Donald E. Ingber1,3,4* Protocols have been established to direct the differentiation of human induced pluripotent stem (iPS) cells into nephro Histology Learning System [ Circulatory System (EM), podocytes and glomerular capillaries

Renal 6, Podocytes and the glomerulus - YouTub

View Podocytes Research Papers on Academia.edu for free Podocytes continually adapt their actin cytoskeleton in response to mechanical stress induced by hydraulic pressure within the glomerulus. Mechanical stress is transmitted to podocytes through cell-matrix contacts, mediated at least in part by the α3β1 integrin, which is required to maintain glomerular structural integrity Aim . Our study is aimed at investigating whether Lipopolysaccharide- (LPS-) treated podocytes could polarize naive CD4 + T cells into different subsets in vitro. Materials and Methods . Podocytes and mouse bone marrow-derived dendritic cells (BMDCs) were first cultured with 25 μ g/ml LPS for 6 hours, respectively إليك 4 نصائح من شأنها أن تساعدك على تحسين النطق لـ 'podocytes' قسم 'podocytes' الي أصوات:: قلها بصوت عالي وبالغ في الأصوات حتى تتمكن من قولها باستمرار سجل نفسك و انت تنطق 'podocytes' في عبارة، وبعدها شاهد نفسك و استمع α-galactosidase A Activity Assay. Podocytes were collected from culture dishes and lysed in PBS by five cycles of freezing and thawing. α-gal A activity was fluorimetrically determined by incubating aliquots of the supernatant at 37°C with 4-methylumbelliferyl α-D-galactopyranoside as substrate (Sigma, Taufkirchen, Germany) as previously described

The Inability of Podocytes to Proliferate: Cause

Introduction. Diabetic nephropathy (DN) is a serious and common complication of diabetes type I and II, leading to end-stage renal disease (ESRD) (1,2).Accumulating evidence suggested that glomerular podocytes have a pivotal role in the pathogenesis of diabetic kidney disease (3,4).Podocytes are terminally differentiated cells residing on the outer surface of the glomerular basement membrane. Abstract. TGF-β is a pleiotropic cytokine that accumulates during kidney injuries, resulting in various renal diseases. We have reported previously that TGF-β1 induces the selective up-regulation of mitochondrial Nox4, playing critical roles in podocyte apoptosis

Dedifferentiation of Immortalized Human Podocytes in

podocytes Collapsing glomerulopathy predominantly afflicts patients of African ancestry, often first presenting after the immune system is engaged by another disorder. Nichols et al. now show that collateral induction of pathogenic APOL1 allelic variants in podocytes by the ongoing immune response may be the long-sought-after explanation for. The ability to derive podocytes from renewable sources, such as stem cells, could help advance current understanding of the mechanisms of human kidney development and disease, as well as provide new tools for therapeutic discovery. The goal of this protocol was to develop a method to derive mature, post-mitotic podocytes from human induced. Podocytes were seeded into the upper layer of the Transwell chamber pre-coated with type I collagen. 12 days later, the podocytes were serum starved overnight and received LPS induction or transfection. After that, the podocytes were wa-shed with phosphate- buffered saline (PBS) (Beyo-time, Shanghai, China) containing 1 mmol/L CaCl 2 and MgCl

Glomerular capillary surrounded by podocytes - PurposeGames

Break 'podocytes' down into sounds: say it out loud and exaggerate the sounds until you can consistently produce them. Record yourself saying 'podocytes' in full sentences, then watch yourself and listen. You'll be able to mark your mistakes quite easily. Look up tutorials on Youtube on how to pronounce 'podocytes' podocyteの意味や使い方 被蓋細胞; 足細胞; 被がい細胞; 有足細胞; おおい細胞 - 約1161万語ある英和辞典・和英辞典。発音・イディオムも分かる英語辞書 www.uptodate.co Methods: MPC5 podocytes were treated with control or high glucose (HG) medium, and then miR-106a level was measured. MPC5 cells that exposed to HG were overexpressed with miR-106a or not, following by overexpression with or without KLF9 or SNHG16. Then, cell viability, apoptosis, reactive oxygen species and the protein expression of. podocytes injury, and agents attenuating podocytes in-jury would be potential therapeutic drugs that prevent against PM2.5-induced MN. Immunosuppressive therapy is widely used for MN, in-cluding corticosteroids, cyclophosphamide, chlorambu-cil, anti-proliferative agents (AP) such as azathioprin

1 ways to abbreviate Conditionally Immortalized Mouse Podocytes. How to abbreviate Conditionally Immortalized Mouse Podocytes? Get the most popular abbreviation for Conditionally Immortalized Mouse Podocytes updated in 202 Podocytes are pivotal in maintaining glomerular filtration barrier function; thus, alterations in these cells are associated with massive proteinuria (13,14). Podocytes are well-differentiated cells with no capacity to divide. The intracellular degradation system is thus believed to be important in maintaining podocyte homeostasis Podocytes consist of cell bodies, major processes and foot processes of neighbouring cells, with filtration slits being bridged by the slit membrane between these filtration slits. The function of podocytes is largely based on their specialized cell architecture ; functions include stabilization of glomerular capillaries and participation in.

(PDF) Podocytes: Way to G

Podocytes are similar to neurons in that they are terminally differentiated cells and have extremely limited proliferative capacity. When injury and loss occur, podocytes cannot proliferate to cope with the adverse living environment, and thus the podocyte response mechanism must adjust to outside stress for survival . Cell autophagy is a. Emodin mitigates podocytes apoptosis induced by endoplasmic reticulum stress through the inhibition of the PERK pathway in diabetic nephropathy Nianxiu Tian,1 Yanbin Gao,1 Xiaolei Wang,1 Xiaoming Wu,2 Dawei Zou,3 Zhiyao Zhu,3 ZheJi Han,1 Tao Wang,1 Yimin Shi1 1Department of Endocrinology, School of Traditional Chinese Medicine, Capital Medical University, Fengtai District, Beijing, China. Podocyte injury and repair mechanisms Current Opinion i

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Diabetic nephropathy (DN) is the primary reason of chronic kidney disease. The aim of our study is to explore the role and action mechanism of M2 macrophage‐derived exosomes in high glucose (HG)‐indu.. We performed a similar analysis with human-derived podocytes with native ABIN1 or ABIN1[D472N] (D485N homologue) stimulated with TNF-α and found that MCP1, IL-8 and TNF-α mRNA expression was enhanced in ABIN1[D472N] podocytes. ELISA results showed that TNF-α-induced secretion of MCP1, IL-8 and TNF-α was also enhanced in ABIN1[D472N] cells

Urinary System ReadingDiabetes Induced Changes in Podocyte Morphology and GeneProximal Tubulopathy: Prime Mover and Key TherapeuticSIU SOM Histology CRRThe Urinary System | Basicmedical Key
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